Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MERTK | Q12866 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900393 | 0.86 | SYK (0.47) | MEN1KMT2A | |
| SCHEMBL8889835 | 0.83 | NPY5R (0.43) | NPY5RPIN1 | |
| SCHEMBL8899460 | 0.83 | NPY5R (0.70) | NPY5RMEN1KMT2ANPC1MERTK | |
| SCHEMBL8900365 | 0.82 | SLC2A1 (0.49) | NPY5RMEN1KMT2ANPC1MERTK | |
| Hydrochloric Acid SCHEMBL6039207 | 0.82 | NPY5R (0.69) | NPY5RMEN1KMT2ANPC1MERTK | |
| Hydrochloric Acid SCHEMBL6039334 | 0.82 | NPY5R (0.69) | NPY5RMEN1KMT2ANPC1MERTK | |
| SCHEMBL8893955 | 0.81 | NPY5R (0.40) | NPY5RMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8898845 | 0.77 | NPY5R (0.41) | NPY5RMEN1KMT2ABRD4POLB | |
| Hydrochloric Acid SCHEMBL8905477 | 0.76 | NPY5R (0.40) | NPY5RMEN1KMT2ABRD4POLB | |
| SCHEMBL8900176 | 0.73 | NPY5R (0.53) | NPY5RMERTKSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |