Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781776 | 0.99 | L3MBTL1 (0.78) | L3MBTL1 | |
| SCHEMBL6629239 | 0.96 | L3MBTL1 (0.73) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL30945299 | 0.91 | L3MBTL1 (0.69) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9434778 | 0.88 | L3MBTL1 (0.78) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9434959 | 0.88 | L3MBTL1 (0.78) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL8863680 | 0.87 | L3MBTL1 (0.76) | L3MBTL1 | |
| SCHEMBL13823926 | 0.87 | L3MBTL1 (0.72) | L3MBTL1 | |
| SCHEMBL1751201 | 0.85 | L3MBTL1 (0.69) | L3MBTL1 | |
| SCHEMBL8300753 | 0.85 | L3MBTL1 (0.69) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL12643699 | 0.85 | L3MBTL1 (0.64) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777471-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |