Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003338 | 0.88 | MEN1 (0.56) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9820417 | 0.86 | MEN1 (0.57) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9820416 | 0.86 | MEN1 (0.57) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL455776 | 0.82 | RAD51 (0.56) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL455775 | 0.82 | RAD51 (0.56) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL670637 | 0.82 | RAD51 (0.56) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL29356717 | 0.82 | RAD51 (0.56) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL22003616 | 0.82 | RAD51 (0.67) | ENPP2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL26725600 | 0.81 | CD40 (0.53) | KMT2AMAPTMEN1ALDH1A1RAB9A | |
| SCHEMBL7744489 | 0.81 | RAD51 (0.55) | ENPP2KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681832-A | FOR TREATMENT OF VIRAL DISEASES BY SUPPRESSING REPLICATION OF RETROVIRUSES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996025399-A1 | NOVEL AROYLANILINE DERIVATIVES, COMPOSITIONS AND USES THEREOF IN THE TREATMENT OF VIRAL INFECTIONS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-22 | — | — | WO | disclosed |