Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 4/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 3/20 | 0.32 |
| ▸ | MDM4 | O15151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889934 | 0.88 | KMT2A (0.40) | KMT2ATLR2MDM2BMP1TNF | |
| SCHEMBL3419719 | 0.86 | KMT2A (0.40) | KMT2ATLR2MDM2BMP1MDM4 | |
| SCHEMBL890352 | 0.84 | ALDH1A1 (0.35) | KMT2AALDH1A1LMNA | |
| SCHEMBL3423921 | 0.82 | KMT2A (0.46) | KMT2ATLR2MDM2BMP1MDM4 | |
| SCHEMBL889833 | 0.82 | KMT2A (0.46) | KMT2ATLR2MDM2BMP1MDM4 | |
| SCHEMBL13782058 | 0.79 | KMT2A (0.46) | KMT2ATLR2MDM2TNFMDM4 | |
| SCHEMBL26231259 | 0.78 | KMT2A (0.43) | KMT2ATLR2MDM2BMP1MDM4 | |
| SCHEMBL13782050 | 0.77 | KMT2A (0.47) | KMT2ATLR2MDM2BMP1MDM4 | |
| SCHEMBL25631518 | 0.76 | KMT2A (0.45) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL6393629 | 0.76 | KMT2A (0.39) | KMT2ATLR2MDM2BMP1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7556923-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-07-07 | — | — | US | disclosed |