Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.52 |
| ▸ | RXRA | P19793 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900282 | 1.00 | PPARG (0.52) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8901026 | 0.84 | PPARG (0.51) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8899525 | 0.83 | PPARG (0.50) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8899528 | 0.83 | PPARG (0.50) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8900757 | 0.82 | PPARG (0.47) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8900212 | 0.82 | PPARG (0.49) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8924867 | 0.82 | PPARG (0.48) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8891390 | 0.82 | PPARG (0.48) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8891797 | 0.81 | PPARG (0.45) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8902387 | 0.81 | PPARG (0.53) | PPARGRXRACYP1A2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |