Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | RXRA | P19793 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | C5 | P01031 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891390 | 1.00 | PPARG (0.48) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8902387 | 0.87 | PPARG (0.53) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8891797 | 0.87 | PPARG (0.45) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8900757 | 0.87 | PPARG (0.47) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8893722 | 0.86 | PPARG (0.44) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8900679 | 0.85 | PPARG (0.45) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8893678 | 0.82 | RXRA (0.43) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8900282 | 0.82 | PPARG (0.52) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8900278 | 0.82 | PPARG (0.52) | PPARGRXRACYP1A2MAPTMAPK1 | |
| SCHEMBL8901396 | 0.81 | PPARG (0.40) | PPARGRXRACYP1A2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | claimed |