Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901338 | 0.82 | NOTUM (0.50) | HSP90AA1PDK2KDM4EKMT2ANPC1 | |
| SCHEMBL6993347 | 0.81 | MEN1 (0.49) | HSP90AA1PDK2POLBKMT2AMEN1 | |
| SCHEMBL9094961 | 0.80 | KMT2A (0.56) | HSP90AA1PDK2KDM4EPOLBKMT2A | |
| Trimethylammonium SCHEMBL27602719 | 0.80 | KDM4E (0.60) | KDM4EPOLBCDC25ACDC25BHSD17B10 | |
| Trimethylammonium SCHEMBL27801332 | 0.80 | KDM4E (0.60) | KDM4EPOLBCDC25ACDC25BHSD17B10 | |
| SCHEMBL5237642 | 0.78 | SRD5A2 (0.48) | HSP90AA1PDK2POLBKMT2AMEN1 | |
| SCHEMBL7333570 | 0.78 | SRD5A2 (0.59) | HSP90AA1PDK2POLBKMT2AMEN1 | |
| SCHEMBL9001684 | 0.78 | PLAU (0.57) | HSP90AA1PDK2KDM4EPOLBKMT2A | |
| SCHEMBL11041431 | 0.78 | NPC1 (0.55) | POLBKMT2AMEN1NPC1TP53 | |
| Terephthalic Acid SCHEMBL29978846 | 0.78 | KDM4E (0.67) | KDM4EPOLBCDC25ACDC25BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |