Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037523 | 0.82 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL8900286 | 0.82 | HSP90AA1 (0.50) | KDM4EHSD17B10HSP90AA1PDK2PDK1 | |
| SCHEMBL9098471 | 0.82 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL820141 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL29699657 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9096918 | 0.78 | NOTUM (0.65) | NOTUMKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL293611 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL4611523 | 0.76 | TSHR (0.63) | NOTUMKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5834949 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL293610 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |