SCHEMBL8900307

SCHEMBL8900307

CCS(=O)(=O)CC1(Cl)C=CC(C(=O)c2ccccc2)=CC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 5/20 0.35
PTGS1 P23219 2/20 0.32
PTGS2 P35354 2/20 0.32
RAB9A P51151 2/20 0.32
ELANE P08246 1/20 0.31
FPR1 P21462 1/20 0.30
HSD17B10 Q99714 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27458451 0.81 ALDH1A1 (0.37) HPGDLMNAALDH1A1RAB9AKMT2A
SCHEMBL27454520 0.81 ALDH1A1 (0.37) HPGDLMNAALDH1A1RAB9AKMT2A
SCHEMBL27475352 0.80 ALDH1A1 (0.33) HPGDLMNAALDH1A1RAB9A
SCHEMBL1952089 0.79 ALDH1A1 (0.35) HPGDALDH1A1RAB9A
SCHEMBL27437816 0.78 ALDH1A1 (0.34) HPGDLMNAALDH1A1KMT2A
SCHEMBL27628328 0.77 NPC1 (0.38) HPGDALDH1A1RAB9AKMT2A
SCHEMBL27513057 0.76 KMT2A (0.35) HPGDLMNAALDH1A1PTGS1PTGS2
SCHEMBL27661013 0.76 ALDH1A1 (0.39) HPGDLMNAALDH1A1RAB9AELANE
SCHEMBL156513 0.75 ALDH1A1 (0.42) HPGDLMNAALDH1A1RAB9AHSD17B10
SCHEMBL8506854 0.74 ALDH1A1 (0.38) HPGDLMNAALDH1A1RAB9AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0766666-A1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-04-09 EP disclosed