Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29233050 | 1.00 | KMT2A (0.59) | KMT2AMEN1HSD17B10ALDH1A1MITF | |
| SCHEMBL18132374 | 0.92 | POLB (0.56) | KMT2AMEN1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL27513166 | 0.92 | POLB (0.56) | KMT2AMEN1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL14426507 | 0.91 | ALDH1A1 (0.62) | KMT2AMEN1HSD17B10ALDH1A1MITF | |
| SCHEMBL12700356 | 0.90 | HSD17B10 (0.55) | KMT2AMEN1HSD17B10ALDH1A1MITF | |
| SCHEMBL18132373 | 0.90 | MEN1 (0.58) | KMT2AMEN1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6851324 | 0.90 | KMT2A (0.56) | KMT2AMEN1HSD17B10ALDH1A1MITF | |
| SCHEMBL3757836 | 0.89 | KMT2A (0.69) | KMT2AMEN1HSD17B10ALDH1A1MITF | |
| SCHEMBL9158022 | 0.89 | MEN1 (0.62) | KMT2AMEN1HSD17B10ALDH1A1MITF | |
| SCHEMBL9157758 | 0.89 | MEN1 (0.62) | KMT2AMEN1HSD17B10ALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |