Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2348771 | 0.83 | PSMD10 (0.41) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL20128922 | 0.81 | CYP24A1 (0.39) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL13886464 | 0.80 | ALDH1A1 (0.41) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL283084 | 0.80 | ALDH1A1 (0.41) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL15270828 | 0.78 | CA12 (0.40) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL6853749 | 0.78 | ALDH1A1 (0.38) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL6852562 | 0.78 | ALDH1A1 (0.38) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL4588419 | 0.78 | PSMD10 (0.39) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL2244715 | 0.78 | PSMD10 (0.39) | PSMD10CA12CA1CA9ALDH1A1 | |
| SCHEMBL5854898 | 0.78 | PSMD10 (0.39) | PSMD10CA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612325-A | ANTIINFLAMMATORY AND IMMUNOMODULATING EFFECTS | Leo Pharmaceutical Products Ltd. A/S (L.o slashed.vens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1997-03-18 | — | — | US | disclosed |