Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | PRCP | P42785 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901616 | 1.00 | HTR1A (0.59) | HTR1ASIGMAR1SRD5A1DRD2PRCP | |
| SCHEMBL8901539 | 0.80 | HTR1A (0.64) | HTR1ADRD2 | |
| SCHEMBL8901535 | 0.80 | HTR1A (0.64) | HTR1ADRD2 | |
| SCHEMBL8901537 | 0.80 | HTR1A (0.64) | HTR1ADRD2 | |
| SCHEMBL8901899 | 0.80 | HTR1A (0.64) | HTR1ADRD2 | |
| SCHEMBL8902000 | 0.78 | HTR1A (0.67) | HTR1ADRD2 | |
| SCHEMBL8901985 | 0.74 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8901989 | 0.74 | HTR1A (1.00) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8899975 | 0.73 | HTR1A (0.97) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8901650 | 0.73 | HTR1A (0.97) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |