Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791394 | 0.80 | — | — | |
| SCHEMBL1006667 | 0.80 | — | — | |
| SCHEMBL1519059 | 0.76 | — | — | |
| SCHEMBL9698363 | 0.74 | SLC7A5 (0.39) | SLC7A5LMNAMAPTXBP1ATM | |
| SCHEMBL5543015 | 0.74 | TET2 (0.32) | — | |
| SCHEMBL6062458 | 0.74 | — | — | |
| SCHEMBL30888062 | 0.73 | — | — | |
| SCHEMBL2915534 | 0.73 | LMNA (0.46) | SLC7A5LMNAMAPTXBP1ATM | |
| SCHEMBL2995714 | 0.73 | — | — | |
| SCHEMBL23313 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800541-A1 | SILOXANE-CONTAINING NETWORKS | Novartis AG (CH) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020964-A1 | SILOXANE-CONTAINING NETWORKS | NOVARTIS AG (CH) | 1996-07-11 | — | — | WO | disclosed |