Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899367 | 0.92 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8898984 | 0.89 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16536381 | 0.88 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3120535 | 0.87 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1070990 | 0.87 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL72841 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8899379 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25812313 | 0.83 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537268 | 0.83 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537063 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |