Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900490 | 0.92 | TSHR (0.57) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL3503924 | 0.88 | TSHR (0.60) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL140538 | 0.88 | TSHR (0.60) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL8898984 | 0.87 | TSHR (0.54) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL16536381 | 0.86 | TSHR (0.54) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL72364 | 0.86 | TSHR (0.62) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL8924216 | 0.86 | TSHR (0.62) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL8900512 | 0.86 | TSHR (0.62) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL7710883 | 0.84 | TSHR (0.55) | TSHRTHRBALDH1A1POLBTDP1 | |
| SCHEMBL1269736 | 0.83 | TSHR (0.58) | TSHRTHRBALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |