Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902029 | 0.93 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL8900589 | 0.91 | EDNRA (0.65) | EDNRAEDNRB | |
| SCHEMBL8901337 | 0.90 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8902138 | 0.89 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL8902400 | 0.87 | EDNRB (0.65) | EDNRAEDNRB | |
| SCHEMBL9046516 | 0.82 | EDNRB (0.52) | EDNRAEDNRB | |
| SCHEMBL8039429 | 0.82 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL8856638 | 0.79 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL8856822 | 0.79 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL8900567 | 0.79 | EDNRA (0.57) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994014434-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | claimed |
| US-5686481-A | INDOLE DERIVATIVES; TREATING HYPERTENSION, RENAL FAILURE, CEREBROVASCULAR DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1994014434-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |