Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | MERTK | Q12866 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889981 | 0.87 | MERTK (0.48) | NPY5RMERTKRAD52KCNH3 | |
| SCHEMBL8900176 | 0.81 | NPY5R (0.53) | NPY5RMERTKSLC2A1ABCG2 | |
| Hydrochloric Acid SCHEMBL8890869 | 0.80 | NPY5R (0.52) | NPY5RSLC2A1KCNH3 | |
| SCHEMBL8891253 | 0.80 | SYK (0.51) | TP53MAPTNPY5RKCNH3 | |
| SCHEMBL8900365 | 0.77 | SLC2A1 (0.49) | TP53MAPTNPY5RMERTKSLC2A1 | |
| SCHEMBL8899460 | 0.77 | NPY5R (0.70) | TP53MAPTNPY5RMERTKSLC2A1 | |
| SCHEMBL8891826 | 0.77 | NPY5R (0.71) | NPY5RMERTKSLC2A1 | |
| Hydrochloric Acid SCHEMBL6039207 | 0.76 | NPY5R (0.69) | TP53MAPTNPY5RMERTKSLC2A1 | |
| Hydrochloric Acid SCHEMBL6039334 | 0.76 | NPY5R (0.69) | TP53MAPTNPY5RMERTKSLC2A1 | |
| SCHEMBL8889361 | 0.76 | KDM4E (0.70) | MAPTNPY5RMERTKSLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |