Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851118 | 0.83 | POLB (0.54) | POLBTSHRALKBH5BRD9LMNA | |
| SCHEMBL30731240 | 0.81 | LMNA (0.57) | POLBTSHRBRD9LMNAALDH1A1 | |
| SCHEMBL8144111 | 0.81 | LMNA (0.57) | POLBTSHRBRD9LMNAALDH1A1 | |
| SCHEMBL849389 | 0.74 | POLB (0.48) | POLBTSHRALKBH5CTSGCMA1 | |
| SCHEMBL849335 | 0.73 | POLB (0.50) | POLBTSHRALKBH5CTSGCMA1 | |
| SCHEMBL850675 | 0.73 | POLB (0.47) | POLBTSHRALKBH5CTSGCMA1 | |
| SCHEMBL11848233 | 0.73 | POLB (0.47) | POLBTSHRALKBH5CTSGCMA1 | |
| SCHEMBL5495891 | 0.71 | POLB (0.48) | POLBTSHRALKBH5CMA1LMNA | |
| SCHEMBL848539 | 0.71 | POLB (0.69) | POLBTSHRALKBH5LMNAALDH1A1 | |
| SCHEMBL19263703 | 0.71 | POLB (0.65) | POLBTSHRALKBH5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |