Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20875236 | 0.86 | ATM (0.60) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL8669692 | 0.86 | ATM (0.60) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL21436777 | 0.85 | TSHR (0.69) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL22584823 | 0.85 | TSHR (0.69) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL5857260 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL9185807 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL5857249 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL25174772 | 0.84 | ATM (0.64) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL20875241 | 0.84 | ATM (0.58) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL28872434 | 0.84 | ATM (0.58) | TSHRALDH1A1CYP3A4ATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639546-A | CURED LAYER OF A CROSSLINKED POLYMER MATRIX AND DISPERSED COLLOIDAL METAL OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0475592-A2 | Coated article having improved adhesion to organic coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4885332-A | WITH POLYACRYLOYL MONOMER AND FREE RADICAL INITIATOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0337695-A2 | Abrasion resistant coatings comprising silicon dioxide dispersions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-18 | — | — | EP | disclosed |