Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110454 | 0.88 | TDP1 (0.55) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL1165204 | 0.87 | TDP1 (0.48) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL28552805 | 0.85 | KMT2A (0.45) | ALDH1A1KDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL18930912 | 0.82 | AVPR2 (0.49) | TDP1ALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4239469 | 0.79 | TDP1 (0.57) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL21412711 | 0.79 | PPARG (0.57) | ALDH1A1KDM4EHPGDPOLBHDAC3 | |
| SCHEMBL14337887 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL6107860 | 0.79 | TDP1 (0.51) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL8900742 | 0.79 | TDP1 (0.59) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL3821707 | 0.79 | MAPT (0.53) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |