Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059353 | 0.89 | GAA (0.50) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL28103035 | 0.87 | HTT (0.52) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL12963121 | 0.85 | ICMT (0.45) | MAPTKMT2AMEN1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL10440705 | 0.84 | HTT (0.54) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL423387 | 0.84 | MAPT (0.56) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL30480119 | 0.84 | MAPT (0.56) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL14180556 | 0.84 | ALDH1A1 (0.49) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL15934274 | 0.84 | TUBB4A (0.57) | ALDH1A1GAAKMT2AMEN1CYP1A2 | |
| SCHEMBL9595593 | 0.83 | HDAC3 (0.46) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL8348474 | 0.83 | KDM4E (0.51) | MAPTALDH1A1GAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857790-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | KANEKA CORP (JP) | 2005-08-17 | — | — | EP | claimed |
| US-20010031487-A1 | Process for producing optically active amino compounds | KANEKA CORPORATION | 2001-10-18 | — | — | US | claimed |
| US-6221638-B1 | BY STEREOSELECTIVELY CARRYING OUT AMINO GROUP TRANSFER BY ACTION OF AN (R)-FORM-SPECIFIC TRANSAMINASE IN THE CO-PRESENCE OF A KETONE (AMINO ACCEPTOR) AND AMINO COMPOUND (AMINO DONOR); YIELDS AMINO COMPOUNDS HAIVNG ARYL GROUP AT THE 1-POSITION | KANEKA CORPORATION (JP) | 2001-04-24 | — | — | US | claimed |
| EP-0857790-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | KANEKA CORPORATION (JP) | 1998-08-12 | — | — | EP | claimed |
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7868205-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |
| EP-0987332-B1 | DNA encoding a polypeptide having stereoselective transaminase activity, and transformants comprising said DNA | KANEKA CORP (JP) | 2009-08-19 | — | — | EP | disclosed |
| US-7569676-B2 | Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | METHYLGENE, INC. (CA) | 2008-06-05 | — | — | US | disclosed |
| EP-1498415-B1 | Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs | ROCHE DIAGNOSTICS GMBH (DE) | 2007-06-27 | — | — | EP | disclosed |
| US-20020192786-A1 | Producing optically active amino compounds | KANEKA CORPORATION | 2002-12-19 | — | — | US | disclosed |
| US-20020132743-A1 | Transparent bar soap composition | P&PF CO., LTD. (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1219701-A1 | Transparent bar soap composition | Shiseido Honecake Industry Co., Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6344351-B2 | USING (R)-FORM-SPECIFIC TRANSAMINASE WITH KETONE AMINO ACCEPTOR AND AMINO DONOR; ANTIDIABETES AND ANTIOBESITY AGENTS | KANEKA CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| US-20010031487-A1 | Process for producing optically active amino compounds | KANEKA CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-6221638-B1 | BY STEREOSELECTIVELY CARRYING OUT AMINO GROUP TRANSFER BY ACTION OF AN (R)-FORM-SPECIFIC TRANSAMINASE IN THE CO-PRESENCE OF A KETONE (AMINO ACCEPTOR) AND AMINO COMPOUND (AMINO DONOR); YIELDS AMINO COMPOUNDS HAIVNG ARYL GROUP AT THE 1-POSITION | KANEKA CORPORATION (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0987332-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | Kaneka Corporation (JP) | 2000-03-22 | — | — | EP | disclosed |
| EP-0857790-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | KANEKA CORPORATION (JP) | 1998-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132743-A1 | Transparent bar soap composition | SGMS1, PHOSPHO1, SGMS2 | MAPT 3125/4885ALDH1A1 1921/4885GAA 2801/4885 |
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC3 | MAPT 2110/4885ALDH1A1 796/4885GAA 210/4885 |
| US-20020192786-A1 | Producing optically active amino compounds | TKT, GOT1, AADAT | MAPT 3031/4885ALDH1A1 151/4885GAA 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.