Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083608 | 0.92 | CCR6 (0.58) | CCR6PAX8ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27343331 | 0.91 | CCR6 (0.56) | CCR6PAX8ALDH1A1LMNAPKM | |
| SCHEMBL28271583 | 0.90 | CCR6 (0.58) | CCR6PAX8ALDH1A1LMNAPKM | |
| SCHEMBL18594775 | 0.89 | CCR6 (0.52) | CCR6PAX8ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11429803 | 0.89 | LMNA (0.57) | ALDH1A1LMNAPKMHDAC1HDAC6 | |
| Carbamic Acid SCHEMBL25282587 | 0.88 | CCR6 (0.55) | CCR6PAX8ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL13687190 | 0.87 | LMNA (0.62) | CCR6PAX8ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27364470 | 0.87 | CCR6 (0.55) | CCR6PAX8ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18057682 | 0.86 | CCR6 (0.60) | CCR6PAX8ALDH1A1LMNAPKM | |
| SCHEMBL13661129 | 0.86 | CCR6 (0.57) | CCR6PAX8ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813543-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028464-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-19 | — | — | WO | disclosed |