SCHEMBL8901010

SCHEMBL8901010

NCCc1occ2cc(Cl)ccc12

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 2/20 0.40
TAAR1 Q96RJ0 4/20 0.38
HTR2A P28223 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
MAOB P27338 3/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
DPP4 P27487 2/20 0.33
FERMT2 Q96AC1 2/20 0.32
PNMT P11086 1/20 0.32
CYP2A6 P11509 1/20 0.31
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2090817 0.79 CYP2A6 (0.33) MAOBCYP2A6
SCHEMBL2092321 0.78
SCHEMBL5545178 0.75 PTPN1 (0.33)
SCHEMBL971316 0.74 HTR2A (0.37) TAAR1HTR2ALOXL2CYP2A6HTR2C
SCHEMBL27610289 0.71
SCHEMBL10962570 0.69 TAAR1 (0.33) TAAR1LOXL2
SCHEMBL19459378 0.68 CYP2A6 (0.37) MAOBCYP2A6
SCHEMBL2090137 0.68 POLB (0.40) MAOBCYP2A6
SCHEMBL6239414 0.66 KDM4E (0.46) MAOB
SCHEMBL7618939 0.66 LMNA (0.42) HTR2APNMTCYP2A6HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0767780-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 1997-04-16 EP disclosed
WO-1996000718-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-01-11 WO disclosed