Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343853 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL13612710 | 0.91 | ALDH1A1 (0.43) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL18994459 | 0.91 | ALDH1A1 (0.43) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL14228910 | 0.83 | ACE (0.53) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL17787724 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL8903845 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL7135300 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL4177794 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL13991694 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDGLARECQLKMT2A | |
| SCHEMBL8958026 | 0.78 | RECQL (0.47) | ALDH1A1HPGDGLARECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326709-B2 | Bicyclic and tricyclic heteroaromatic compounds | NEUROGEN CORPORATION (US) | 2008-02-05 | — | — | US | disclosed |
| US-5623082-A | REACTING CARBOXYLIC ACID OR ITS ANHYDRIDE WITH CARBONYL CHLORIDE IN PRESENCE OF DI-SEC-BUTYLFORMAMIDE OR DI-3-PENTYLFORMAMIDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0340706-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC-ACID CHLORIDES | BASF Aktiengesellschaft (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0340706-A2 | Process for the preparation of carboxylic-acid chlorides | BASF Aktiengesellschaft (DE) | 1989-11-08 | — | — | EP | disclosed |
| US-4137305-A | TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4137304-A | TOPICAL OR ORAL ADMINISTERED TOBACCO PRODUCT | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4136164-A | FOR USE IN FOODS, TOPICAL PREPARATIONS, AND TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-23 | — | — | US | disclosed |