Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505079 | 0.87 | AKR1C3 (0.52) | PTPN11 | |
| SCHEMBL6941556 | 0.82 | MAPK1 (0.72) | MAPK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6043409 | 0.81 | MAPK1 (0.48) | MAPK1PTPN11PDE4APDE4BPDE4C | |
| SCHEMBL1353135 | 0.81 | CA1 (0.59) | MAPK1HTTKDM4EALDH1A1PARP10 | |
| SCHEMBL30151541 | 0.81 | MAPK1 (0.50) | MAPK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1505305 | 0.80 | PTGDR2 (0.55) | PTPN11KMT2AKDM4EALDH1A1PTK2B | |
| SCHEMBL1505121 | 0.80 | KDM4E (0.52) | PTPN11KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL7089733 | 0.80 | PTPN11 (0.49) | MAPK1PTPN11KMT2AKDM4ES1PR3 | |
| SCHEMBL18300979 | 0.79 | TSHR (0.49) | PTPN11KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL9448372 | 0.79 | MAPK1 (0.51) | MAPK1KMT2AHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |