SCHEMBL8901323

SCHEMBL8901323

O=C(O)c1ccccc1Br.O=S(=O)(Cl)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 1/20 0.52
PRNP P04156 1/20 0.49
TSHR P16473 1/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA12 O43570 2/20 0.45
CA4 P22748 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
HPGD P15428 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HMGB1 P09429 1/20 0.45
CA6 P23280 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
CA14 Q9ULX7 1/20 0.45
KMT2A Q03164 2/20 0.45
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49806 0.89 ALDH1A1 (0.65) ALDH1A1ALOX15PRNPTSHRCA1
SCHEMBL27236820 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
SCHEMBL8613579 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
SCHEMBL2112435 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
SCHEMBL17799574 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
SCHEMBL6820162 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
Fluoride SCHEMBL27985469 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
Hydrochloric Acid SCHEMBL1586914 0.87 ALDH1A1 (0.62) ALDH1A1ALOX15PRNPTSHRCA1
Methyl Alcohol SCHEMBL38658039 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15PRNPCA1CA2
SCHEMBL11658576 0.82 ALDH1A1 (0.76) ALDH1A1ALOX15PRNPTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693461-A GELATIN-GRAFTED-POLYMER PARTICLES AND SILVER HALIDE GELATIN-PARTICLES; HETEROFLOCCULATED EMULSION; AT LEAST ONE OF THE PEPTIZING AND GRAFTED GELATINS IS AN ISOING GELATIN EASTMAN KODAK COMPANY (US) 1997-12-02 US disclosed
US-5486451-A FORMING A DISPERSION OF SILVER HALIDE GRAINS IN THE PRESENCE OF A HYDROPHILIC COLLOID AND REMOVING BY-PRODUCTS BY LOWERING THE PH TO BRING ABOUT COAGULATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-23 US disclosed
EP-0645672-A1 Method for preparing silver halide photographic emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-29 EP disclosed