Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 1.00 |
| ▸ | HTR1B | P28222 | 13/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901608 | 1.00 | HTR1D (1.00) | HTR1DHTR1BALDH1A1LMNANOS3 | |
| SCHEMBL8903278 | 0.88 | HTR1B (1.00) | HTR1DHTR1BNOS3NOS1SLC6A4 | |
| SCHEMBL8903284 | 0.88 | HTR1B (1.00) | HTR1DHTR1BNOS3NOS1SLC6A4 | |
| SCHEMBL8893980 | 0.83 | HTR1D (0.73) | HTR1DHTR1BSLC6A4 | |
| SCHEMBL27191666 | 0.80 | HTR1D (0.67) | HTR1DHTR1BSLC6A4HTR1AHTR7 | |
| SCHEMBL8686765 | 0.80 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL27206330 | 0.80 | HTR1D (0.67) | HTR1DHTR1BSLC6A4HTR1AHTR7 | |
| SCHEMBL8686525 | 0.80 | HTR1B (0.67) | HTR1DHTR1BNOS3NOS1HTR1A | |
| SCHEMBL8688634 | 0.80 | HTR1B (0.67) | HTR1DHTR1BNOS3NOS1HTR1A | |
| SCHEMBL8688640 | 0.80 | HTR1B (0.67) | HTR1DHTR1BNOS3NOS1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |