Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 9/20 | 0.73 |
| ▸ | HTR1B | P28222 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901901 | 0.85 | HTR1D (1.00) | HTR1DHTR1BBRD4 | |
| SCHEMBL8901608 | 0.83 | HTR1D (1.00) | HTR1DHTR1BSLC6A4 | |
| SCHEMBL8901617 | 0.83 | HTR1D (1.00) | HTR1DHTR1BSLC6A4 | |
| SCHEMBL8686765 | 0.83 | HTR1D (1.00) | HTR1DHTR1BHTR2ABRD4 | |
| SCHEMBL8903278 | 0.83 | HTR1B (1.00) | HTR1DHTR1BHTR2ADRD2HTR2C | |
| SCHEMBL8903284 | 0.83 | HTR1B (1.00) | HTR1DHTR1BHTR2ADRD2HTR2C | |
| SCHEMBL8903385 | 0.82 | HTR1D (0.98) | HTR1DHTR1BHTR2ABRD4 | |
| SCHEMBL8902545 | 0.77 | HTR1D (1.00) | HTR1DHTR1BHTR2ABRD4 | |
| SCHEMBL8686525 | 0.77 | HTR1B (0.67) | HTR1DHTR1B | |
| SCHEMBL8688640 | 0.77 | HTR1B (0.67) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |