Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903349 | 0.82 | NQO1 (0.32) | NQO1 | |
| SCHEMBL8901498 | 0.82 | NQO1 (0.32) | NQO1 | |
| SCHEMBL11130086 | 0.66 | BCL2 (0.61) | NQO1KDM4EMEN1KMT2APTPN1 | |
| SCHEMBL11041307 | 0.65 | NQO1 (0.40) | NQO1 | |
| SCHEMBL8903145 | 0.61 | NQO1 (0.38) | NQO1KDM4EMEN1KMT2A | |
| SCHEMBL14567025 | 0.61 | NQO1 (0.54) | NQO1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL8901799 | 0.61 | NQO1 (0.37) | NQO1KDM4EMEN1KMT2A | |
| SCHEMBL14567024 | 0.61 | NQO1 (0.57) | NQO1KDM4EMEN1KMT2APTPN1 | |
| SCHEMBL8901769 | 0.61 | NQO1 (0.41) | NQO1PTPN1 | |
| SCHEMBL8901643 | 0.61 | NQO1 (0.33) | NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |