Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901643 | 0.85 | NQO1 (0.33) | NQO1 | |
| SCHEMBL8901799 | 0.81 | NQO1 (0.37) | NQO1IDO1ALOX5HPGDALDH1A1 | |
| SCHEMBL8900228 | 0.80 | TCF4 (0.39) | IDO1HPGDALDH1A1MAPTHSP90AA1 | |
| SCHEMBL8901769 | 0.79 | NQO1 (0.41) | NQO1IDO1ALOX5MAOAPGAM1 | |
| SCHEMBL8903047 | 0.79 | NQO1 (0.40) | NQO1ALOX5ALDH1A1SLC37A4MEN1 | |
| SCHEMBL8903328 | 0.79 | NQO1 (0.40) | NQO1ALOX5ALDH1A1SLC37A4MEN1 | |
| SCHEMBL8902939 | 0.77 | NQO1 (0.37) | NQO1IDO1ALOX5HPGDALDH1A1 | |
| SCHEMBL8903683 | 0.77 | NQO1 (0.37) | NQO1IDO1ALOX5HPGDALDH1A1 | |
| SCHEMBL8901558 | 0.75 | DNMT3B (0.44) | NQO1IDO1ALOX5MAOAPGAM1 | |
| SCHEMBL8901552 | 0.74 | NQO1 (0.38) | NQO1ALOX5HPGDALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |