⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531428 | 0.69 | — | — | |
| SCHEMBL8903142 | 0.67 | IDO1 (0.33) | — | |
| SCHEMBL26597757 | 0.67 | BRD3 (0.31) | — | |
| SCHEMBL14140476 | 0.67 | — | — | |
| SCHEMBL11809519 | 0.67 | — | — | |
| SCHEMBL8527887 | 0.66 | — | — | |
| SCHEMBL8527892 | 0.65 | — | — | |
| SCHEMBL8532252 | 0.63 | — | — | |
| SCHEMBL8528056 | 0.63 | MAOA (0.33) | — | |
| SCHEMBL8900585 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |