Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27354248 | 0.83 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL8531831 | 0.81 | NLRP3 (0.31) | — | |
| SCHEMBL8900992 | 0.81 | — | — | |
| SCHEMBL8901566 | 0.76 | — | — | |
| SCHEMBL21847497 | 0.75 | BRD4 (0.38) | MIFALDH1A1HTTBRD4KMT2A | |
| SCHEMBL8901724 | 0.74 | MIF (0.33) | MIFALDH1A1HTTBRD4 | |
| SCHEMBL8913965 | 0.74 | MIF (0.33) | MIFALDH1A1HTTBRD4 | |
| SCHEMBL8900793 | 0.69 | AKT1 (0.34) | MIF | |
| SCHEMBL20939850 | 0.69 | HDAC3 (0.43) | MIFALDH1A1KMT2A | |
| SCHEMBL10982547 | 0.69 | BRD4 (0.40) | ALDH1A1BRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |