SCHEMBL8901754

SCHEMBL8901754

CC1N(C)C(=O)N(C)C1(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.38
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
PABPC1 P11940 1/20 0.34
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28949212 0.76
SCHEMBL12659702 0.76 KMT2A (0.41) ADRA2CKMT2AMEN1PABPC1
SCHEMBL13993376 0.76 KMT2A (0.41) ADRA2CKMT2AMEN1PABPC1
SCHEMBL9680515 0.65
SCHEMBL12670022 0.63 ADRA2C (0.36) ADRA2CKMT2AMAPK1
SCHEMBL16997421 0.63 GAA (0.33) ADRA2C
SCHEMBL12702950 0.61
SCHEMBL3949214 0.61 ADRA2C (0.33) ADRA2CKMT2AMEN1PABPC1
SCHEMBL23590431 0.60
SCHEMBL11050863 0.60 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618951-A REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT ELI LILLY AND COMPANY (US) 1997-04-08 US claimed
JP-7252231-A None JP disclosed
US-5618951-A REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT ELI LILLY AND COMPANY (US) 1997-04-08 US disclosed
JP-H07252231-A PRODUCTION OF 2-IMIDAZOLIDINONES MITSUI TOATSU CHEM INC 1995-10-03 JP disclosed
US-4918186-A Process for producing cyclic ureas MITSUI TOATSU CHEMICALS, INC. (JP) 1990-04-17 US disclosed
US-4900820-A REACTING UREA WITH ACYCLIC DIAMINE MITSUI TOATSU CHEMICALS, INC. (JP) 1990-02-13 US disclosed
EP-0249136-A2 Process for producing cyclic ureas MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-12-16 EP disclosed
EP-0248220-A2 Process for producing cyclic ureas MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-12-09 EP disclosed
US-4448969-A Cyclic ether or carbonate alkylation products of 2,2,5,5-tetramethylimidazolidin-4-one and derivatives, their preparation, and their use as stabilizers for _synthetic polymers FERRO CORPORATION (US) 1984-05-15 US disclosed