Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901552 | 1.00 | NQO1 (0.38) | NQO1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8901512 | 0.89 | NQO1 (0.36) | NQO1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8903328 | 0.88 | NQO1 (0.40) | NQO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8903047 | 0.88 | NQO1 (0.40) | NQO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9755794 | 0.88 | NQO1 (0.42) | NQO1GPR84ALOX5PGAM1 | |
| SCHEMBL8902819 | 0.86 | KDM4E (0.34) | MAPTKMT2AHPGDKDM4EGPR84 | |
| SCHEMBL8902587 | 0.86 | KDM4E (0.34) | MAPTKMT2AHPGDKDM4EGPR84 | |
| SCHEMBL8903683 | 0.82 | NQO1 (0.37) | NQO1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8902939 | 0.82 | NQO1 (0.37) | NQO1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8901799 | 0.82 | NQO1 (0.37) | NQO1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |