Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902587 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1HPGDNPSR1NPC1 | |
| SCHEMBL9755764 | 0.92 | ADORA3 (0.35) | KDM4EALDH1A1HPGDNPSR1NPC1 | |
| SCHEMBL8902842 | 0.90 | ALDH1A1 (0.35) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL8902600 | 0.90 | ALDH1A1 (0.35) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL8901762 | 0.86 | NQO1 (0.38) | KDM4EALDH1A1HPGDNPSR1GPR84 | |
| SCHEMBL8901552 | 0.86 | NQO1 (0.38) | KDM4EALDH1A1HPGDNPSR1GPR84 | |
| SCHEMBL8901727 | 0.83 | KDM4E (0.34) | KDM4EALDH1A1HPGDNPSR1NPC1 | |
| SCHEMBL9520715 | 0.82 | KDM4E (0.33) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9521041 | 0.82 | KDM4E (0.33) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8903426 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |