Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519005 | 0.75 | GRIK1 (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20312145 | 0.74 | CYP1A2 (0.52) | DPP4F2 | |
| SCHEMBL30374537 | 0.72 | NFE2L2 (0.62) | NFE2L2RELA | |
| SCHEMBL9967705 | 0.72 | NFE2L2 (0.62) | NFE2L2RELA | |
| SCHEMBL2870524 | 0.72 | NFE2L2 (0.62) | NFE2L2RELA | |
| SCHEMBL2234105 | 0.72 | NFE2L2 (1.00) | NFE2L2GRM4RELA | |
| SCHEMBL3722628 | 0.71 | NFE2L2 (0.60) | NFE2L2RELAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL18321193 | 0.69 | NFE2L2 (0.58) | NFE2L2RELA | |
| SCHEMBL27514141 | 0.69 | NFE2L2 (0.71) | NFE2L2GRM4RELAGRIN2DGRIN3B | |
| SCHEMBL23934880 | 0.67 | DPP4 (0.46) | DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686622-A | Thiazolidine derivatives, their preparation and the medicaments containing the same | RHONE-POULENC RORER S.A. (FR) | 1997-11-11 | — | — | US | disclosed |