Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903420 | 1.00 | KDM4E (0.35) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL8903879 | 0.95 | KDM4E (0.36) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL9755777 | 0.88 | HTT (0.36) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL8901690 | 0.88 | HTT (0.36) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL8902124 | 0.88 | HTT (0.36) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL9755783 | 0.87 | HTT (0.36) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL8902600 | 0.84 | ALDH1A1 (0.35) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL8902842 | 0.84 | ALDH1A1 (0.35) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL9521698 | 0.82 | KDM4E (0.37) | KDM4EGAAHTTMAPTHSD17B10 | |
| SCHEMBL8903426 | 0.82 | KDM4E (0.37) | KDM4EGAAHTTMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |