Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902945 | 0.96 | NQO1 (0.38) | NQO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8903687 | 0.96 | NQO1 (0.38) | NQO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8901731 | 0.85 | ADORA3 (0.35) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL8901799 | 0.75 | NQO1 (0.37) | NQO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8903534 | 0.72 | ADORA3 (0.33) | KMT2AALDH1A1MAPTPOLBGAA | |
| SCHEMBL8901769 | 0.71 | NQO1 (0.41) | NQO1ALOX5 | |
| SCHEMBL8903683 | 0.71 | NQO1 (0.37) | NQO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8902939 | 0.71 | NQO1 (0.37) | NQO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11041307 | 0.69 | NQO1 (0.40) | NQO1HPGDALOX5 | |
| SCHEMBL8901834 | 0.69 | NQO1 (0.32) | NQO1MEN1KMT2ANR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |