Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 4/20 | 0.40 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25507305 | 0.92 | ACKR3 (0.44) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL25507697 | 0.91 | ACKR3 (0.43) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL1715473 | 0.91 | ACKR3 (0.43) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL24568430 | 0.88 | ACKR3 (0.45) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL4202607 | 0.82 | USP2 (0.47) | ACKR3TLR8EPHX2USP2SMN1; SMN2 | |
| SCHEMBL8253901 | 0.81 | USP2 (0.51) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL16744141 | 0.80 | USP2 (0.43) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL20873847 | 0.79 | USP2 (0.53) | ACKR3TLR8EPHX2USP2SMN1; SMN2 | |
| SCHEMBL15585975 | 0.79 | TLR8 (0.42) | ACKR3KMT5ATLR8EPHX2USP2 | |
| SCHEMBL8145651 | 0.79 | TLR8 (0.42) | ACKR3KMT5ATLR8EPHX2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017338-A1 | SUBSTITUTED 1-INDOLYLPROPYL-4-BENZYLPIPERAZINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-15 | — | — | WO | disclosed |