Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902507 | 0.87 | FAAH (0.33) | FAAHTSHR | |
| SCHEMBL15741889 | 0.83 | TSHR (0.40) | ACHETSHR | |
| SCHEMBL168598 | 0.82 | TSHR (0.50) | FAAHTSHRNAAA | |
| SCHEMBL8351897 | 0.81 | TSHR (0.57) | ACHECASP2CNR1FAAHTSHR | |
| SCHEMBL28078386 | 0.79 | TSHR (0.60) | ACHEFAAHTSHRNAAA | |
| Methacrylic Acid SCHEMBL725335 | 0.79 | TSHR (0.51) | FAAHTSHRNAAA | |
| SCHEMBL17063567 | 0.79 | TSHR (0.60) | ACHEFAAHTSHRNAAA | |
| SCHEMBL6274865 | 0.79 | TSHR (0.60) | ACHEFAAHTSHRNAAA | |
| SCHEMBL14660709 | 0.79 | TSHR (0.60) | ACHEFAAHTSHRNAAA | |
| SCHEMBL459709 | 0.77 | TSHR (0.50) | ACHEFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639546-A | CURED LAYER OF A CROSSLINKED POLYMER MATRIX AND DISPERSED COLLOIDAL METAL OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-17 | — | — | US | disclosed |