Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049356 | 0.82 | TDP1 (0.47) | TDP1USP2HTTTSHRHSD17B10 | |
| SCHEMBL20590292 | 0.77 | TSHR (0.46) | TDP1USP2HTTTSHRSPHK1 | |
| SCHEMBL8769656 | 0.76 | TDP1 (0.37) | TDP1HSD17B10 | |
| SCHEMBL20582052 | 0.76 | HTT (0.50) | USP2HTTTSHRSPHK1 | |
| SCHEMBL4889663 | 0.75 | TDP1 (0.38) | TDP1USP2HTTTSHRHSD17B10 | |
| SCHEMBL9657933 | 0.73 | TSHR (0.46) | TDP1USP2HTTTSHRHSD17B10 | |
| SCHEMBL5467568 | 0.72 | TDP1 (0.39) | TDP1USP2HTTHSD17B10 | |
| SCHEMBL106780 | 0.71 | — | — | |
| SCHEMBL11581242 | 0.70 | TSHR (0.54) | TDP1TSHRHSD17B10 | |
| SCHEMBL29204613 | 0.70 | HSD17B10 (0.44) | TDP1USP2HTTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618854-A | Combustion-modified flexible polyurethane foams | THE DOW CHEMICAL COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0496420-B1 | Combustion-modified flexible polyurethane foams | DOW CHEMICAL CO (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0496420-A2 | Combustion-modified flexible polyurethane foams | THE DOW CHEMICAL COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |