Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 13/20 | 0.74 |
| ▸ | CCR3 | P51677 | 5/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | HRH2 | P25021 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107267 | 0.85 | CCR1 (1.00) | CCR1CCR3 | |
| SCHEMBL6067579 | 0.85 | CCR1 (0.69) | CCR1CCR3OPRM1ADRA2ADRD4 | |
| SCHEMBL9105318 | 0.85 | OPRM1 (0.87) | CCR1CCR3OPRM1ADRA2ADRD4 | |
| SCHEMBL8891231 | 0.85 | CCR1 (1.00) | CCR1CCR3OPRM1 | |
| Berlex Compound SCHEMBL8891715 | 0.83 | CCR1 (1.00) | CCR1CCR3 | |
| Berlex Compound SCHEMBL29401934 | 0.82 | CCR1 (0.98) | CCR1CCR3 | |
| SCHEMBL8986084 | 0.82 | CCR1 (0.68) | CCR1CCR3OPRM1 | |
| SCHEMBL9105079 | 0.82 | CCR1 (1.00) | CCR1CCR3 | |
| SCHEMBL9108706 | 0.81 | CCR1 (1.00) | CCR1CCR3 | |
| SCHEMBL8986035 | 0.81 | CCR1 (0.67) | CCR1CCR3OPRM1SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |