Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.54 |
| ▸ | HTR1D | P28221 | 12/20 | 0.53 |
| ▸ | HTR1B | P28222 | 12/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482078 | 0.82 | MAPT (0.53) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL8604076 | 0.80 | NOS1 (0.55) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL7485162 | 0.79 | HTR1D (0.58) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL27527198 | 0.79 | HTR1D (0.58) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL8605118 | 0.79 | NOS1 (0.52) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL8578087 | 0.78 | NOS1 (0.57) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL27482162 | 0.77 | HTR1D (0.56) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL8427311 | 0.77 | HTR1B (0.50) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL27481048 | 0.77 | HTR1D (0.55) | NOS1HTR1DHTR1BMAPTBLM | |
| SCHEMBL27483636 | 0.76 | HTR1D (0.48) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691791-A | Reflective liquid crystal display device and reflector | SHARP KABUSHIKI KAISHA (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559617-A | Liquid crystal display device with overlapping compensators with portions having different retardation values | SHARP KABUSHIKI KAISHA (JP) | 1996-09-24 | — | — | US | disclosed |