Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075409 | 0.79 | KDM4E (0.41) | KDM4ELMNAALDH1A1KDM5BTSHR | |
| SCHEMBL8994051 | 0.73 | GSK3B (0.56) | SMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL11825534 | 0.73 | TSHR (0.46) | KDM4ELMNAALDH1A1KDM5BTSHR | |
| SCHEMBL16592150 | 0.70 | MAOA (0.44) | — | |
| SCHEMBL27370401 | 0.69 | BACE1 (0.47) | KDM4ELMNAALDH1A1KDM5BTSHR | |
| SCHEMBL844040 | 0.69 | KDM4E (0.40) | SMN1; SMN2KDM4ELMNAALDH1A1KDM5B | |
| SCHEMBL16592145 | 0.69 | HTR2C (0.64) | SMN1; SMN2HTTKDM4ELMNATSHR | |
| SCHEMBL16592133 | 0.69 | GRM5 (0.37) | SMN1; SMN2HTTKDM4EALDH1A1TSHR | |
| SCHEMBL16592129 | 0.68 | HTR2C (0.42) | KDM4EPOLBL3MBTL1DHODHEGFR | |
| SCHEMBL16592155 | 0.68 | HTR2C (0.43) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |