Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573435 | 0.88 | CA12 (0.67) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL11158120 | 0.87 | PKM (0.53) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL10721933 | 0.87 | PKM (0.56) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL28899597 | 0.85 | CISD1 (0.66) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL7797968 | 0.84 | KDM4E (0.65) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL7801303 | 0.83 | KDM4E (0.63) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL10723753 | 0.81 | KDM4E (0.61) | KDM4ENPSR1PKMLCKFYN | |
| SCHEMBL11688578 | 0.81 | PKM (0.70) | KDM4EPKMCA12CA1CA2 | |
| SCHEMBL11710380 | 0.81 | PKM (0.50) | KDM4ENPSR1PKMCA12CA1 | |
| SCHEMBL11159006 | 0.80 | KDM4E (0.60) | KDM4ENPSR1PKMLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0068700-A1 | Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |