Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800763 | 0.97 | LMNA (0.42) | LMNATHRBTSHRALDH1A1DPP4 | |
| SCHEMBL9506729 | 0.97 | LMNA (0.42) | LMNATHRBTSHRALDH1A1DPP4 | |
| SCHEMBL17951325 | 0.97 | LMNA (0.42) | LMNATHRBTSHRALDH1A1DPP4 | |
| SCHEMBL4445441 | 0.91 | LMNA (0.50) | LMNATHRBTSHRALDH1A1 | |
| SCHEMBL1054310 | 0.88 | LMNA (0.37) | LMNATSHRALDH1A1 | |
| SCHEMBL12678041 | 0.86 | LMNA (0.36) | LMNATSHRALDH1A1 | |
| SCHEMBL4893457 | 0.86 | SMN1; SMN2 (0.41) | LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1168877 | 0.86 | LMNA (0.41) | LMNATHRBTSHRALDH1A1 | |
| SCHEMBL4400624 | 0.84 | — | — | |
| SCHEMBL1051714 | 0.84 | LMNA (0.39) | LMNATHRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646236-A | POLYAMINE REACTANT; METAL ELECTRODEPOSITION BATHS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-08 | — | — | US | claimed |