SCHEMBL8902156

SCHEMBL8902156

CCC(CC[C]=O)N1CCN(C)CC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MC4R P32245 3/20 0.34
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3588742 0.78 MC4R (0.38) MC4RIDO1
SCHEMBL26178209 0.78 MC4R (0.38) MC4RIDO1
SCHEMBL9927907 0.77 IDO1 (0.41) MC4RIDO1
SCHEMBL13635723 0.75 MC4R (0.36) MC4RIDO1
SCHEMBL3585361 0.75 MC4R (0.41) MC4RIDO1
SCHEMBL3585010 0.75 MC4R (0.41) MC4RIDO1
SCHEMBL3593558 0.75 MC4R (0.41) MC4RIDO1
SCHEMBL8902161 0.74 MC4R (0.34) MC4RIDO1
SCHEMBL1128494 0.73 CYP1A2 (0.39) MC4RIDO1
SCHEMBL24069487 0.72 IDO1 (0.36) MC4RIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5610315-A Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1997-03-11 US disclosed
US-5484954-A HEATING, DEACYLATING NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-01-16 US disclosed
US-5302730-A Acylation with acetic acid at positions one and seven; eliminating acyl group at position seven by solvolysis NIPPON KAYAKU KK (JP) 1994-04-12 US disclosed
EP-0297496-B1 Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KK (JP) 1994-01-19 EP disclosed
US-5245052-A PROCESS FOR PRODUCING 6-ACYL-7-DEACETYLFORSKOLIN DERIVATIVES NIPPON KAYAKU CO. LTD. (JP) 1993-09-14 US disclosed
CN-1060291-A The novel method of preparation 6-acyl group-7-deacetylforskolin derivatives HOECHST JAPAN (JP) 1992-04-15 CN disclosed
EP-0469428-A1 Novel process for producing 6-acyl-7-deacetylforskolin derivatives HOECHST JAPAN LIMITED (JP) 1992-02-05 EP disclosed
EP-0297496-A2 Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-01-04 EP disclosed