Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585007 | 0.83 | MC4R (0.35) | MC4RIDO1ALDH1A1KDM4ETDP1 | |
| SCHEMBL3585357 | 0.83 | MC4R (0.35) | MC4RIDO1ALDH1A1KDM4ETDP1 | |
| SCHEMBL3588742 | 0.78 | MC4R (0.38) | MC4RIDO1ALDH1A1KDM4E | |
| SCHEMBL26178209 | 0.78 | MC4R (0.38) | MC4RIDO1ALDH1A1KDM4E | |
| SCHEMBL9927907 | 0.77 | IDO1 (0.41) | MC4RIDO1ALDH1A1KDM4E | |
| SCHEMBL13635723 | 0.75 | MC4R (0.36) | MC4RIDO1 | |
| SCHEMBL3593558 | 0.75 | MC4R (0.41) | MC4RIDO1ALDH1A1KDM4ETDP1 | |
| SCHEMBL3585010 | 0.75 | MC4R (0.41) | MC4RIDO1ALDH1A1KDM4ETDP1 | |
| SCHEMBL3585361 | 0.75 | MC4R (0.41) | MC4RIDO1ALDH1A1KDM4ETDP1 | |
| SCHEMBL8902156 | 0.74 | MC4R (0.34) | MC4RIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610315-A | Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5484954-A | HEATING, DEACYLATING | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1996-01-16 | — | — | US | disclosed |
| US-5302730-A | Acylation with acetic acid at positions one and seven; eliminating acyl group at position seven by solvolysis | NIPPON KAYAKU KK (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0297496-B1 | Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KK (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5245052-A | PROCESS FOR PRODUCING 6-ACYL-7-DEACETYLFORSKOLIN DERIVATIVES | NIPPON KAYAKU CO. LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0469428-A1 | Novel process for producing 6-acyl-7-deacetylforskolin derivatives | HOECHST JAPAN LIMITED (JP) | 1992-02-05 | — | — | EP | disclosed |
| EP-0297496-A2 | Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | disclosed |