Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103359 | 0.90 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL19845013 | 0.87 | TSHR (0.60) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7740688 | 0.87 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5078976 | 0.85 | TSHR (0.62) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1398258 | 0.85 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9328527 | 0.84 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL23493924 | 0.83 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12266939 | 0.83 | ALOX15 (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12198799 | 0.83 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1899131 | 0.83 | TSHR (0.58) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639546-A | CURED LAYER OF A CROSSLINKED POLYMER MATRIX AND DISPERSED COLLOIDAL METAL OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0475592-A2 | Coated article having improved adhesion to organic coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |