SCHEMBL8902306

SCHEMBL8902306

COC(=O)c1cc(N)c(OC)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.67
KDM4E B2RXH2 7/20 0.65
POLB P06746 3/20 0.54
ALDH1A1 P00352 7/20 0.49
HSD17B10 Q99714 4/20 0.49
HPGD P15428 3/20 0.49
MAPT P10636 2/20 0.49
GLA P06280 2/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
ATM Q13315 1/20 0.49
CFTR P13569 2/20 0.48
CYP3A4 P08684 1/20 0.48
ABL1 P00519 1/20 0.47
KMT2A Q03164 1/20 0.47
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568484 0.92 KDM4E (0.76) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL29424850 0.90 GAA (0.74) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL6473999 0.90 GAA (0.74) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL31305136 0.90 KDM4E (0.72) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL2900351 0.89 KDM4E (0.82) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL31430552 0.85 GAA (0.63) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL11385067 0.85 GAA (0.63) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL31615884 0.85 KDM4E (0.61) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL8902601 0.84 GAA (0.54) GAAKDM4EPOLBALDH1A1HSD17B10
SCHEMBL23874532 0.84 GAA (0.61) GAAKDM4EPOLBALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025120168-A1 SULFONAMIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CRYPTOSPORIDIUM INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2025-06-12 WO disclosed
US-5686482-A DOPAMINE RECEPTOR ANTAGONIST YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1997-11-11 US disclosed
EP-0757985-A1 N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-02-12 EP disclosed